SPRM (Surface Plasmon Resonance Microscopy) is a powerful technology that enables label-free kinetic binding interaction studies of drug molecules with whole cells in real-time. By combining traditional cell culture and imaging techniques with standard biophysical assays, SPRM enables direct measurements of the interaction between drug compound and membrane receptors while in their native whole-cell environment. This unique approach delivers more biologically relevant information about drug target interactions.
In this webinar, Pfizer will show how they utilized SPRM along with other biophysical techniques to characterize ligand and antibody binding to CCRL2. We will also provide an overview of the SPRM technology with a variety of small molecule and antibody binding examples.
Learning Objectives
- Describe principles of SPRM
- Review case studies of small molecule and antibody binding
- Discover about label-free GPCR binding affinity and kinetics on whole cells
Looking forward “seeing” you at the webinar!
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